have you got any "Any component" block? (when any Button.Click for example)
Because when it was a independent screen this kind of blocks works only with the screen buttons but now, if you are joining screens into "virtual screens" that "when any Button.Click" will affect to all the buttons of the screen (even for those in other arrangements).
So now you need to handle game buttons separately from the others buttons of the other virtual screens.
For example, try to protect that block to be executed only if you arrangement where you are displaying the game is visible (the virtual screen of the game is visible):
(it is an example, whatever the arrangement is called where you have the paired numbers game)